Synthetic Polymers as Drug-Delivery Vehicles in Medicine

Synthetic Polymers as Drug-Delivery Vehicles in Medicine

Cancerous diseases present a formidable health problem worldwide. While the chemotherapy of cancer, in conjunction with other treatment modalities, has reached a significant level of maturity, efficacious use of such agents is still restricted by numerous pharmacological deficiencies, such as poor water solubility, short serum circulation lifetimes, and low bioavailability resulting from lack o...

Imprinted polymers as drug delivery vehicles for anti-inflammatory drugs

The aim of this work was to investigate the possibility of employing semi-covalent molecularly imprinted polymers (MIPs) as a controlled release device for ibuprofen and naproxen in biological fluids, especially gastrointestinal ones, compared to non imprinted polymers (NIPs). The carboxyl groups of ibuprofen and naproxen were converted to vinyl ester group by reacting ibuprofen and vinyl aceta...

Polymeric micelles as drug delivery vehicles

Nerve guidance channels as drug delivery vehicles.

Nerve guidance channels (NGCs) have been shown to facilitate regeneration after transection injury to the peripheral nerve or spinal cord. Various therapeutic molecules, including neurotrophic factors, have improved regeneration and functional recovery after injury when combined with NGCs; however, their impact has not been maximized partly due to the lack of an appropriate drug delivery system...

Polymers in Drug Delivery

Polymers are being used extensively in drug delivery due to their surface and bulk properties. They are being used in drug formulations and in drug delivery devices. These drug delivery devices may be in the form of implants for controlled drug delivery. Polymers used in colloidal drug carrier systems, consisting of small particles, show great advantage in drug delivery systems because of optim...